Fact Check: Are PDO threads worth it?

Fact Check: Are PDO threads worth it?

Published May 7, 2025
±
VERDICT
Partially True

# Are PDO Threads Worth It? The claim in question revolves around the effectiveness and value of PDO (Polydioxanone) threads in facial rejuvenation p...

Are PDO Threads Worth It?

The claim in question revolves around the effectiveness and value of PDO (Polydioxanone) threads in facial rejuvenation procedures. PDO threads are absorbable sutures used in non-surgical facelift techniques, purported to lift and tighten the skin while stimulating collagen production. As the popularity of these treatments grows, so does the inquiry into whether they provide significant benefits relative to their costs and risks.

What We Know

  1. Mechanism and Use: PDO threads are designed to be inserted into the skin to provide a lifting effect and promote collagen production. They are often marketed as a non-surgical alternative to traditional facelifts, with claims of immediate and long-lasting results 47.

  2. Scientific Literature: A review of the scientific literature indicates that while PDO threads are widely used, there is a lack of rigorous studies validating their effectiveness. A 2023 literature review highlighted that very few studies have been conducted that meet high scientific standards 4.

  3. Patient Satisfaction: Some studies report high levels of patient satisfaction with PDO thread lifts, particularly when combined with other procedures like blepharoplasty and mid-face lifts 2. However, these studies often have methodological limitations, such as small sample sizes or lack of control groups.

  4. Risks and Limitations: Critics of PDO thread lifts point out that the initial lifting effect can diminish within a few months, and there may be risks associated with the procedure, including infection, scarring, and uneven results 10.

  5. Industry Influence: Some studies supporting the efficacy of PDO threads have been funded by manufacturers of the threads, raising concerns about potential bias in the findings 46.

Analysis

The evidence surrounding PDO threads is mixed and warrants careful consideration.

  • Source Reliability: The studies cited in the literature review 4 and the case reports 9 provide some insights into the effectiveness of PDO threads. However, the reliance on manufacturer-sponsored research introduces a potential conflict of interest, which can skew results in favor of the product.

  • Methodological Concerns: Many of the studies lack rigorous methodologies, such as randomized controlled trials, which are the gold standard in clinical research. For instance, while some articles report positive outcomes, they often do not adequately control for variables that could affect results, such as patient demographics or the specific techniques used by practitioners 18.

  • Expert Opinions: Medical professionals have expressed varied opinions on PDO threads. While some practitioners praise their effectiveness and ease of use 7, others caution against the hype, noting that the results may not be as enduring as advertised 10. This divergence suggests that individual experiences may vary significantly based on practitioner skill and patient characteristics.

  • Additional Information Needed: More comprehensive studies with larger sample sizes and longer follow-up periods would be beneficial to better understand the long-term efficacy and safety of PDO threads. Additionally, independent studies not funded by manufacturers would help clarify the true effectiveness of these procedures.

Conclusion

Verdict: Partially True

The claim regarding the effectiveness and value of PDO threads in facial rejuvenation is deemed "Partially True." Evidence suggests that while PDO threads may provide some lifting effect and patient satisfaction, the scientific literature lacks robust studies to fully validate these claims. Many studies are limited by small sample sizes, methodological flaws, and potential biases due to industry funding.

It is important to note that while some patients report positive outcomes, the longevity of these results is often questioned, and risks associated with the procedure cannot be overlooked. The mixed opinions among medical professionals further highlight the uncertainty surrounding PDO threads.

Readers should approach this information critically, recognizing that the effectiveness of PDO threads may vary based on individual circumstances and practitioner expertise. Continued research is necessary to provide clearer insights into the long-term efficacy and safety of these treatments.

Sources

  1. Using PDO threads: A scarcely studied rejuvenation technique. Case ... (https://pubmed.ncbi.nlm.nih.gov/37021458/)
  2. Advanced Facial Rejuvenation: Synergistic Effects of Lower ... (https://pmc.ncbi.nlm.nih.gov/articles/PMC11093801/)
  3. Facial rejuvenation - Wikipedia (https://en.wikipedia.org/wiki/Facial_rejuvenation)
  4. How a PDO Thread Lift Works, How Long It Lasts, Risks & More - RealSelf (https://www.realself.com/nonsurgical/thread-lift)
  5. PDF Outcomes of Polydioxanone Knotless Thread Lifting for Facial Rejuvenation (https://lesencres.com/wp-content/uploads/2023/02/PDO.pdf)
  6. How a PDO Thread Lift Works, How Long It Lasts, Risks & More (https://www.realself.com/nonsurgical/thread-lift#:~:text=A%20literature%20review%20published%20in,%2C%20and%2C%20also%2C%20on%20the)
  7. Intraline PDO Threads Reviews and Techniques - Medical SPA RX (https://www.medicalsparx.com/intraline-pdo-threads/)
  8. Using PDO threads: A scarcely studied rejuvenation technique. Case ... (https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.15709)
  9. Efficacy of Polydioxanone Threads for The Treatment of Facial Sagging ... (https://revistaft.com.br/efficacy-of-polydioxanone-threads-for-the-treatment-of-facial-sagging-case-report/)
  10. Don't Believe the Hype About PDO Thread Lifts (https://www.greenwichmedicalspa.com/2023/06/01/dont-believe-the-hype-about-pdo-thread-lifts)

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