Fact Check: Twice-yearly lenacapavir shot shows no infections in young women, unlike daily pills.

Fact Check: Twice-yearly lenacapavir shot shows no infections in young women, unlike daily pills.

Published June 19, 2025
by TruthOrFake AI
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# Fact Check: "Twice-yearly lenacapavir shot shows no infections in young women, unlike daily pills." ## What We Know Lenacapavir, a long-acting inje...

Fact Check: "Twice-yearly lenacapavir shot shows no infections in young women, unlike daily pills."

What We Know

Lenacapavir, a long-acting injectable drug developed by Gilead Sciences, has recently been approved by the FDA as the first twice-yearly shot for HIV prevention. Clinical trials have demonstrated its efficacy, particularly among young women and adolescent girls. In one significant study involving over 5,300 participants in South Africa and Uganda, there were no reported HIV infections among those receiving the lenacapavir shot, while approximately 2% of those taking daily pills (PrEP) contracted the virus (AP News, NPR, ABC News). This suggests that lenacapavir may offer a more effective alternative to daily oral PrEP, which has been shown to have adherence issues leading to reduced effectiveness in some populations (NPR).

Analysis

The claim that "twice-yearly lenacapavir shot shows no infections in young women, unlike daily pills" is supported by robust clinical trial data. The study referenced involved a direct comparison between lenacapavir and daily oral PrEP, demonstrating a significant difference in infection rates. The trials were conducted rigorously, with a large sample size and a focus on populations at high risk for HIV, enhancing the reliability of the findings (WHO, Gilead).

However, while the results are promising, it's essential to consider the broader context. The effectiveness of lenacapavir is not solely due to the drug itself but also involves factors such as access to healthcare, stigma associated with HIV prevention methods, and the overall public health infrastructure (AP News, NBC News). Critics have raised concerns about the high cost of the drug, which could limit access for many individuals who would benefit from it (NPR, USA Today).

The sources used in this analysis are credible, including major news outlets and health organizations, which provide a balanced view of the drug's potential and the challenges ahead. The studies cited are peer-reviewed and conducted by reputable researchers, adding to the reliability of the claims made regarding lenacapavir's effectiveness.

Conclusion

The claim that the twice-yearly lenacapavir shot shows no infections in young women, unlike daily pills, is True. The clinical trials clearly indicate that lenacapavir has a significantly higher efficacy in preventing HIV infections compared to daily oral PrEP, particularly in the studied demographic. However, the success of this new treatment will depend on addressing issues related to access, cost, and healthcare infrastructure.

Sources

  1. The world’s only twice-a-year shot to prevent HIV ...
  2. HIV prevention drug hailed as a 'breakthrough' gets FDA ...
  3. Long-acting injectable lenacapavir proves effective in HIV ...
  4. FDA approves the world’s only twice-a-year shot to prevent HIV
  5. Yeztugo Lenacapavir Is Now the First and Only FDA ...
  6. Twice-a-year shot to prevent HIV approved in U.S.
  7. FDA approves powerful HIV prevention drug
  8. FDA approves new twice-yearly HIV shot. What to know

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