Fact Check: Is erythritol safe?

Fact Check: Is erythritol safe?

Published July 1, 2025
±
VERDICT
Partially True

# Is Erythritol Safe? ## Introduction The safety of erythritol, a popular sugar substitute, has come under scrutiny recently, with claims suggesting ...

Is Erythritol Safe?

Introduction

The safety of erythritol, a popular sugar substitute, has come under scrutiny recently, with claims suggesting it may pose health risks. This discussion has been fueled by emerging research linking erythritol to potential cardiovascular and cerebrovascular issues, raising questions about its long-term effects on health. This article examines the available evidence regarding erythritol's safety, exploring both supportive and opposing viewpoints.

What We Know

Erythritol is a sugar alcohol that is approximately 30% less sweet than sucrose and contains negligible calories, as it is almost entirely absorbed by the body and excreted in urine [1]. It has been used as a sweetener since the 1990s and is approved by various regulatory agencies, including the FDA and EFSA, for use in food products [2].

However, recent studies have suggested potential health risks associated with erythritol consumption. For instance, a study published in the Journal of Applied Physiology indicated that erythritol could impair brain vascular cell function, raising concerns about its effects on brain health [4]. Additionally, other research has linked higher plasma concentrations of erythritol to increased risks of cardiovascular and cerebrovascular events [6].

WebMD has reported that erythritol might be associated with serious health risks, potentially being worse for health than table sugar [3]. The Cleveland Clinic also highlighted that while erythritol is generally well-tolerated, there are emerging concerns about its impact on heart and brain health [5].

Analysis

The sources reviewed present a mix of historical context and emerging research, which complicates the assessment of erythritol's safety.

  1. Historical Use and Regulatory Approval: Sources like Wikipedia and the NCBI article emphasize erythritol's long history of safe use and regulatory approval, which lends credibility to its safety profile [1][2]. However, these sources may not fully address the recent studies that suggest potential risks.

  2. Emerging Research: The studies cited in sources such as Food Safety News and Medical Xpress raise significant concerns about erythritol's safety, particularly regarding its effects on brain and cardiovascular health [4][6]. These studies appear to be based on epidemiological data and laboratory research, which can indicate correlations but do not establish causation. Furthermore, the potential for bias should be considered, as some research may be funded by entities with vested interests in alternative sweeteners or health products.

  3. Digestive Issues: It is well-documented that sugar alcohols, including erythritol, can cause digestive discomfort in some individuals [8]. This is a recognized side effect, but it does not necessarily correlate with the more severe health risks suggested by recent studies.

  4. Conflicting Information: The contrasting narratives—one emphasizing erythritol's safety based on historical use and regulatory approval, and the other highlighting new research suggesting serious health risks—illustrate the complexity of the issue. The reliability of the newer studies may hinge on their methodology, sample size, and whether they have been peer-reviewed.

  5. Need for Further Research: Given the conflicting evidence, additional studies are necessary to clarify the long-term effects of erythritol consumption. Specifically, randomized controlled trials that assess health outcomes over extended periods would be beneficial in determining any causal relationships.

Conclusion

Verdict: Partially True

The assessment of erythritol's safety is nuanced, with evidence supporting both its historical safety and emerging concerns regarding its potential health risks. On one hand, erythritol has a long history of use and is approved by regulatory agencies, which suggests a level of safety. On the other hand, recent studies indicate possible associations between erythritol consumption and adverse cardiovascular and cerebrovascular effects, raising valid concerns that warrant further investigation.

It is important to note that while some studies suggest potential risks, they often rely on observational data that cannot definitively establish causation. Additionally, the possibility of bias in research funding and methodology should be considered when interpreting these findings.

Given these complexities, the conclusion that erythritol is "Partially True" reflects the current state of knowledge, acknowledging both its established safety profile and the emerging evidence that suggests caution may be warranted.

Readers are encouraged to critically evaluate information regarding erythritol and consult healthcare professionals when making dietary choices, as ongoing research may further illuminate the implications of erythritol consumption.

Sources

  1. Erythritol: An In-Depth Discussion of Its Potential to Be a … NCBI
  2. Erythritol - Wikipedia Wikipedia
  3. Erythritol: Uses, Benefits, and Risks - WebMD WebMD
  4. Sugar substitute could disrupt brain blood flow, researchers warn Food Safety News
  5. What’s Erythritol? And Is It Bad for You? - Cleveland Clinic Health Cleveland Clinic
  6. Major sugar substitute found to impair brain blood vessel cell function Medical Xpress
  7. Popular Sugar Substitute May Harm Brain and Heart Health Physiology.org
  8. Erythritol — Healthy Sweetener or a Big, Fat Lie? Healthline

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