Fact Check: Are hrt patches safe?

Fact Check: Are hrt patches safe?

Published May 8, 2025
±
VERDICT
Partially True

# Are HRT Patches Safe? ## Introduction The safety of hormone replacement therapy (HRT) patches is a topic of significant interest, particularly amon...

Are HRT Patches Safe?

Introduction

The safety of hormone replacement therapy (HRT) patches is a topic of significant interest, particularly among menopausal women seeking relief from symptoms such as hot flashes and vaginal discomfort. The claim under scrutiny is whether HRT patches are safe for use. This article will explore the available evidence, including benefits, risks, and expert opinions, without reaching a definitive conclusion.

What We Know

HRT patches are transdermal systems that deliver hormones, typically estrogen and sometimes progestin, through the skin into the bloodstream. They are commonly used to alleviate menopausal symptoms and prevent osteoporosis in postmenopausal women. According to MedlinePlus, these patches replace hormones that the body no longer produces, helping to manage various menopausal symptoms effectively 1.

The Mayo Clinic notes that systemic estrogen, which can be administered via patches, is absorbed throughout the body and can treat multiple menopause-related issues 4. The NHS states that while there are risks associated with HRT, recent evidence suggests that the benefits often outweigh these risks, particularly when using patches instead of oral medications, which may carry a higher risk of blood clots 10.

However, side effects are a consideration. Healthline mentions that while HRT patches can ease menopausal symptoms, they also come with potential risks, which may include skin irritation and, in some cases, more serious health concerns 9.

Analysis

The sources reviewed provide a range of perspectives on the safety of HRT patches.

  1. Credibility of Sources:

    • MedlinePlus and Mayo Clinic are reputable medical resources that provide evidence-based information. They are generally considered reliable due to their affiliation with government health agencies and established medical institutions.
    • Healthline and NHS also have a solid reputation for providing health information, although they may be more accessible and less formal than government resources.
    • SimplyMenopause and My Menopause Centre offer more anecdotal evidence and personal experiences, which may introduce bias and should be interpreted with caution.
  2. Bias and Reliability:

    • The NHS and Mayo Clinic present a balanced view, emphasizing both benefits and risks, which is crucial for informed decision-making. However, they may also reflect a pro-HRT stance due to the increasing acceptance of HRT in clinical guidelines.
    • SimplyMenopause and similar sources may have a bias towards personal narratives that could skew perceptions of safety, as they often focus on individual experiences rather than large-scale studies.
  3. Methodology and Evidence:

    • The evidence supporting the benefits of HRT patches often comes from clinical studies and guidelines from professional organizations, which are generally robust. However, the long-term effects and safety profiles of HRT patches are still being studied, and ongoing research is necessary to fully understand their implications 8.
    • The claim that the benefits outweigh the risks is supported by recent guidelines, but these guidelines can evolve as new research emerges, indicating that the safety of HRT patches is an area of active inquiry.

Conclusion

Verdict: Partially True

The claim regarding the safety of HRT patches is deemed "Partially True" based on the evidence reviewed. While reputable sources such as MedlinePlus and the Mayo Clinic indicate that HRT patches can effectively alleviate menopausal symptoms and may present fewer risks compared to oral HRT, there are still notable concerns regarding potential side effects and long-term safety.

The evidence suggests that the benefits of HRT patches often outweigh the risks, particularly for certain populations. However, the ongoing research into the long-term effects of HRT patches means that definitive conclusions about their safety cannot yet be made.

It is important to recognize that individual experiences with HRT patches can vary significantly, and personal health factors must be considered. Readers should be aware that while current guidelines support the use of HRT patches, these recommendations may change as new evidence emerges.

As with any medical treatment, it is crucial for individuals to consult healthcare professionals and critically evaluate the information available to them.

Sources

  1. MedlinePlus. "Estrogen and Progestin Transdermal Patch (Hormone Replacement Therapy)." Link
  2. University of Rochester Medical Center. "How long is it safe to continue to use a low-dose estrogen patch?" Link
  3. Medical News Today. "HRT patches: Benefits, side effects, and how to use them." Link
  4. Mayo Clinic. "Menopause hormone therapy: Is it right for you?" Link
  5. Cleveland Clinic. "Estradiol Patch: Uses & Side Effects." Link
  6. My Menopause Centre. "HRT patches information sheet." Link
  7. SimplyMenopause. "HRT Patches Side Effects: 3 Things To Know." Link
  8. University Hospitals. "Is HRT Safe for Menopause? New Guidelines Say Yes." Link
  9. Healthline. "Menopause Patch: The Benefits and the Risks." Link
  10. NHS. "Benefits and risks of hormone replacement therapy (HRT)." Link

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Miller isn’t concerned about the state of New York “society.” What bothers him is the idea of nonwhite people having political power. Bessent isn’t really deeply worried about Zamdani’s economic ideas. But he feels free, maybe even obliged, to slander a foreign-born Muslim with language he would never use about a white Christian politician, even if that politician were (like some of his colleagues in the Trump administration) a total crackpot. And while Tuberville stands out even within his caucus as an ignorant fool, his willingness to use dehumanizing language about millions of people shows that raw racism is rapidly becoming mainstream in American politics. Remember, during the campaign both Trump and JD Vance amplified the slanders about Haitians eating pets. And now that they’re in office, you can see the resurgence of raw racism all across Trump administration policies, large and small. You can see it, for example, in the cuts at the National Institutes of Health, which are so tilted against racial minorities that a federal judge — one appointed by Ronald Reagan! — declared I’ve never seen a record where racial discrimination was so palpable. I’ve sat on this bench now for 40 years. I’ve never seen government racial discrimination like this. You can see it in the renaming of military bases after Confederate generals — that is, traitors who fought for slavery. You can even see it in a change in the military’s shaving policy that is clearly custom-designed to drive Black men — who account for around a quarter of the Army’s new recruits — out of the service. So racism and bigotry are back, big time. Who’s safe? Nobody. Are you a legal immigrant? Well, the Supreme Court just allowed Trump to summarily strip half a million U.S. residents of that status, and only a fool would imagine that this is the end of the story. 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Detailed fact-check analysis of: Paul Krugman Paul Krugman We’re All Rats Now Time to take a stand, again, against racism Paul Krugman Jun 30, 2025 Zohran Mamdani’s upset victory in New York’s Democratic primary has created panic in MAGAland. Stephen Miller, the architect of Donald Trump’s deportation policies, waxed apocalyptic: Scott Bessent, the Treasury secretary, declared that New York is about to turn into “Caracas on the Hudson.” And Sen. Tommy Tuberville of Alabama basically declared New York’s voters subhuman, saying: These inner-city rats, they live off the federal government. And that’s one reason we’re $37 trillion in debt. And it’s time we find these rats and we send them back home, that are living off the American taxpayers that are working very hard every week to pay taxes. These reactions are vile, and they’re also dishonest. Whatever these men may claim, it’s all about bigotry. Miller isn’t concerned about the state of New York “society.” What bothers him is the idea of nonwhite people having political power. Bessent isn’t really deeply worried about Zamdani’s economic ideas. But he feels free, maybe even obliged, to slander a foreign-born Muslim with language he would never use about a white Christian politician, even if that politician were (like some of his colleagues in the Trump administration) a total crackpot. And while Tuberville stands out even within his caucus as an ignorant fool, his willingness to use dehumanizing language about millions of people shows that raw racism is rapidly becoming mainstream in American politics. Remember, during the campaign both Trump and JD Vance amplified the slanders about Haitians eating pets. And now that they’re in office, you can see the resurgence of raw racism all across Trump administration policies, large and small. You can see it, for example, in the cuts at the National Institutes of Health, which are so tilted against racial minorities that a federal judge — one appointed by Ronald Reagan! — declared I’ve never seen a record where racial discrimination was so palpable. I’ve sat on this bench now for 40 years. I’ve never seen government racial discrimination like this. You can see it in the renaming of military bases after Confederate generals — that is, traitors who fought for slavery. You can even see it in a change in the military’s shaving policy that is clearly custom-designed to drive Black men — who account for around a quarter of the Army’s new recruits — out of the service. So racism and bigotry are back, big time. Who’s safe? Nobody. Are you a legal immigrant? Well, the Supreme Court just allowed Trump to summarily strip half a million U.S. residents of that status, and only a fool would imagine that this is the end of the story. Anyway, when masked men who claim to be ICE agents but refuse to show identification are grabbing people off the streets because they think those people look illegal, does legal status even matter? Does it even matter if you’re a U.S. citizen? And the One Big Beautiful Bill Act is set to massively increase ICE’s funding — basically setting up a huge national secret police force. Now, maybe you imagine that you yourself won’t suffer from this new reign of bigotry and imagine that everyone you care about is similarly safe. But if that’s what you think, you’re likely to face a rude awakening. I personally don’t have any illusions of safety. Yes, I’m a native-born white citizen. But my wife and her family are Black, and some of my friends and relatives are foreign-born U.S. citizens. Furthermore, I’m Jewish, and anyone who knows their history realizes that whenever right-wing bigotry is on the ascendant, we’re always next in line. Are there really people out there naïve enough to believe MAGA’s claims to be against antisemitism, who can’t see the transparent cynicism and dishonesty? The fact is that the Trump administration already contains a number of figures with strong ties to antisemitic extremists. The Great Replacement Theory, which has de facto become part of MAGA’s ideology, doesn’t just say that there’s a conspiracy to replace whites with people of color; it says that it’s a Jewish conspiracy. So I’m definitely scared of what the many antisemites inside or with close ties to the Trump administration may eventually do. And no, I’m not frightened at all by the prospect that New York may soon have a somewhat leftist Muslim mayor. Anyway, my personal fears are beside the point. Everyone who cares about keeping America America needs to take a stand against the resurgence of bigotry. Because the truth is that we’re all rats now. MUSICAL CODA Discussion about this post Michael Roseman Jun 30 Edited For a while, American bigotry was ashamed of itself. Or pretended to be. Now it runs the government. Reply Share 106 replies Megan Rothery Jun 30 Edited Take a stand - Call. Write. Email. Protest. Unrelentingly. Use/share this spreadsheet as a resource to call/email/write members of Congress, the Cabinet and news organizations. Reach out to those in your own state, as well as those in others. Use your voice and make some “good trouble” ❤️‍🩹🤍💙 https://docs.google.com/spreadsheets/d/13lYafj0P-6owAJcH-5_xcpcRvMUZI7rkBPW-Ma9e7hw/edit?usp=drivesdk Reply Share 31 replies 852 more comments... No posts Ready for more? © 2025 Paul Krugman Privacy ∙ Terms ∙ Collection notice Start writing Get the app Substack is the home for great culture

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